| 产品详情 |
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| Product Name | PLX-3397 |
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| Description | PLX3397 is a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potential antineoplastic activity. PLX3397 binds to and inhibits phosphorylation of stem cell factor receptor (KIT), colony-stimulating factor-1 receptor (CSF1R) and FMS-like tyrosine kinase 3 (FLT3), which may result in the inhibition of tumor cell proliferation and down-modulation of macrophages, osteoclasts and mast cells involved in the osteolytic metastatic disease. MW: 417.81. Purity ≥98% by HPLC |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 5-((5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl)-N-((6-(trifluoromethyl)pyridin-3-yl)methyl)pyridin-2-amine; Pexidartinib |
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| Gene, Accession, CAS # | CAS: 1029044-16-3 |
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| Catalog # | 9617-10 |
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| Order / More Info | PLX-3397 from BIOVISION, INC. |
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| Product Specific References | n/a |
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