| 产品详情 |
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| Antigenic Specificity | IL-33 |
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| Clone | polyclonal |
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| Host Species | Goat |
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| Reactive Species | mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | ELISA Capture |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-mouse IL-33. IL-33 belongs to the IL-1 family and is closely related in structure to IL-18 and IL-1b. IL-33, IL-1b, and IL-18 are synthesized as biologically inactive precursor and are cleaved by the enzyme caspase-1 to be secreted as active mature forms. IL-33 stimulates target cells by binding to the IL-1R/TLR superfamily member ST2 and subsequently activates NF-κB and MAPK pathways via identical signalling events to those observed for IL-1b. In addition, IL-33 is a nuclear factor (NF-HEV) abundantly expressed in high endothelial venules from lymphoid organs that associates with chromatin and exhibits transcriptional regulatory properties. |
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| Immunogen | Mouse IL-33, amino acids Ser109-Ile266 (Accession# NM_133775) was expressed in E. coli. |
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| Other Names | n/a |
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| Gene, Accession # | Gene ID: 77125 |
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| Catalog # | 516501 |
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| Price | |
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| Order / More Info | IL-33 Antibody from BIOLEGEND |
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| Product Specific References | PubMed: 25429071 |
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| 产品资料 |
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