| 产品详情 |
| Edit |   |
|---|
| Product Name | Recombinant Human sFas Receptor Protein |
|---|
| Description | Fas and Fas Ligand (FasL) belong to the TNF superfamily and are type I and type II transmembrane proteins, respectively. Binding of FasL to Fas triggers apoptosis in Fas-bearing cells. The mechanism of apoptosis involves recruitment of pro-caspase 8 through an adaptor molecule called FADD followed by processing of the pro-enzyme to active forms. These active caspases then cleave various cellular substrates leading to the eventual cell death. sFasR is capable of inhibiting FasL-induced apoptosis by acting as a decoy receptor that serves as a sink for FasL. The full length Fas (receptor) is a 319 amino acid type I transmembrane protein, which contains a 157 amino acid extracellular domain, a 17 amino acid transmembrane domain, and 145 amino acid cytoplasmic domain. Recombinant human soluble Fas (sFas Receptor) is a 157 amino acid polypeptide (17.6 kDa) corresponding to the TNFR homologous cysteine rich extracellular domain Fas. |
|---|
| Size | Various Sizes |
|---|
| Concentration | n/a |
|---|
| Applications | Cell Culture |
|---|
| Other Names | Tumor necrosis factor receptor superfamily member 6;Apo-1 antigen;Apoptosis-mediating surface antigen FAS;FASLG receptor;CD95;FAS;APT1, FAS1, TNFRSF6; soluble Fas receptor (sFasR), TNFRSF6, CD95, Apo I, Fas Antigen |
|---|
| Gene, Accession, CAS # | FAS, UniProt: P25445 |
|---|
| Catalog # | PROTP25445-2 |
|---|
| Price | |
|---|
| Order / More Info | Recombinant Human sFas Receptor Protein from BOSTER BIO |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|