产品详情 |
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Antigenic Specificity | AKT1S1 (phospho T246) |
Clone | BA0306 |
Host Species | Recombinant Rabbit |
Reactive Species | mouse, human |
Isotype | IgG |
Format | purified |
Size | n/a |
Concentration | n/a |
Applications | WB, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit Anti-AKT1S1 (phospho T246) Recombinant Antibody (BA0306). This product is a rabbit antibody that recognizes AKT1S1 (phospho T246). The antibody BA0306 can be used for immunoassay techniques such as: WB, IP. AKT1S1 is a proline-rich substrate of AKT (MIM 164730) that binds 14-3-3 protein when phosphorylated. Akt1s1, which they called Pras40, from rat hepatoma cells. By EST database analysis, they identified mouse and human PRAS40. The deduced 256-amino acid human protein contains 2 N-terminal proline-rich regions and a C-terminal AKT phosphorylation site, thr246, that is conserved in rat and mouse. mTORC1 phosphorylates and activates S6K1 at 'Thr-389', which then promotes protein synthesis by phosphorylating PDCD4 and targeting it for |
Immunogen | Synthetic phosphopeptide from residues surrounding Threonine 246 of Human PRAS40 |
Other Names | AKT1 Substrate 1 (Proline-Rich); 40 KDa Proline-Rich AKT Substrate; PRAS40; Proline-Rich Akt Substrate; 40 KDa; Lobe |
Gene, Accession # | Gene ID: 84335, UniProt: Q96B36 |
Catalog # | CBMAB-0049CQ |
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Order / More Info | AKT1S1 (phospho T246) Antibody from CREATIVE BIOLABS |
Product Specific References | n/a |
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