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| Product Name | Recombinant Macaca fascicularis Legumain (LGMN) |
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| Description | Purity > 85% as determined by SDS-PAGE. MW: 39.7kDa. Full Length of Mature Protein: 18-323aa. N-terminal 10xHis-tagged and C-terminal Myc-tagged. Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey). Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Required for normal lysosomal protein degradation in renal proximal tubules. Required for normal degradation of internalized EGFR. Plays a role in the regulation of cell proliferation via its role in EGFR degradation. May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Asparaginyl endopeptidase; Protease, cysteine 1; Gene namesi; Name:LGMN; PRSC1 |
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| Gene, Accession, CAS # | LGMN, UniProt: Q4R4T8 |
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| Catalog # | RPC25657 |
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| Order / More Info | Recombinant Macaca fascicularis Legumain (LGMN) from BIOMATIK |
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| Product Specific References | n/a |
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