| 产品详情 |
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| Antigenic Specificity | TRAF7 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL, Immunohistochemistry: 1:50-1:200 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TRAF7 Polyclonal Antibody. TRAFs are signal transducers for members of TNFR superfamily. These are critically involved in activation of MAP3K family members involved in NF-kappaB and JNK activation and apoptosis. TRAF7, a novel 670 A.A protein, is a human homolog of mouse Traf7 and consists of an N-terminal RING finger domain, central TRAF domain, a coiled-coil motif and 7 WD40 repeats at the C-terminus. It has E3-ubiquitin ligase activity for self-ubiquitination. TRAF7 specifically interacts with MEKK3 and mediates MEKK3-induced AP1 and CHOP activation and induces apoptosis through Caspase-independent pathways.It is a multifunctional protein involved in sumoylation and negative regulation of c-Myb, thereby regulating proliferation and diff |
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| Immunogen | n/a |
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| Other Names | TNF receptor-associated factor 7, E3 ubiquitin protein ligase, DKFZp586I021, MGC7807, RFWD1, RNF119 |
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| Gene, Accession # | Entrez: 84231; Uniprot: Q6Q0C0 |
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| Catalog # | PA5-59490 |
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| Price | |
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| Order / More Info | TRAF7 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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