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Product Name | Sphingomyelinase Activity Colorimetric Assay Kit |
Description | Sphingomyelinase (SMase) cleaves sphingomyelin to produce phosphocholine and ceramide. The activation of SMase leads to increased production of ceramide, which acts as a lipid second messenger that induces a variety of cell regulatory phenomena such as apoptosis, cell differentiation, cell proliferation, and sterol homeostasis. There are five distinct types of SMases. BioVision's SMase Activity Assay Kit provides a simple and sensitive method for measuring neutral-SMase enzymatic activity using colorimetry (OD 570 nm). Neutral sphingomyelinase (N-SMase) is a Mg2+ sensitive enzyme that can be activated by a host of physiologically relevant and structurally diverse molecules. In this assay, SMase converts sphingomyelin substrate to phosphocho |
Size | 100 assays |
Concentration | n/a |
Applications | • Measurement of SMase activity in various tissues/cells extracts• Screening of SMase inhibitors |
Other Names | n/a |
Gene, Accession, CAS # | n/a |
Catalog # | K599-100 |
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Order / More Info | Sphingomyelinase Activity Colorimetric Assay Kit from BIOVISION, INC. |
Product Specific References | n/a |
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