| 产品详情 |
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| Antigenic Specificity | TRAF2 |
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| Clone | 33A1293 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1, kappa |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:10-1:500, Western Blot: 2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TRAF2 Monoclonal Antibody (33A1293). Tumor necrosis factor (TNF) induced signaling is mediated through association of TNF receptor (TNFR) with adaptor proteins, such as TNF receptor associated proteins (TRAFs). TRAFs form a family of cytoplasmic adapter proteins that mediate signal transduction from many members of the TNF-receptor superfamily (e.g. RANK, CD30, CD40, etc.) and the interleukin-1 receptor. The carboxy-terminal region of TRAFs is required for self-association and interaction with receptor cytoplasmic domains following ligand-induced oligomerization. Recent molecular cloning studies have lead to identification of six TRAFs (TRAF1-TRAF6) (1-4). TRAF2 is a 502-amino acid protein. Mutagenic studies suggest that the N-terminal RING |
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| Immunogen | n/a |
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| Other Names | MGC:45012, TRAP, TRAP3 |
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| Gene, Accession # | Entrez: 7186; Uniprot: Q12933 |
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| Catalog # | MA1-41028 |
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| Price | |
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| Order / More Info | TRAF2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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