| 产品详情 |
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| Antigenic Specificity | TRAF5 |
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| Clone | 55A219 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blot: 2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TRAF5 Monoclonal Antibody (55A219). Tumor necrosis factor (TNF) induced signaling is mediated through association of TNF receptor (TNFR) with adaptor proteins, such as TNF receptor associated proteins (TRAFs). TRAFs form a family of cytoplasmic adapter proteins that mediate signal transduction from many members of the TNF-receptor superfamily (e.g. RANK, CD30, CD40, etc.) and the interleukin-1 receptor. The carboxy-terminal region of TRAFs is required for self-association and interaction with receptor cytoplasmic domains following ligand-induced oligomerization. Recent molecular cloning studies have lead to identification of six TRAFs (TRAF1-TRAF6) (1-4). TRAF5 is a 558-amino acid protein. TRAF5 is implicated in NF-kB and c-Jun NH(2)-termin |
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| Immunogen | n/a |
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| Other Names | MGC:39780, RNF84 |
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| Gene, Accession # | Entrez: 7188; Uniprot: O00463 |
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| Catalog # | MA1-41102 |
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| Price | |
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| Order / More Info | TRAF5 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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