产品详情 |
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Antigenic Specificity | ST2 |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | lyophilized |
Applications | Flow Cytometry: 0.25 µg/1x10^6 cells, Neutralization: 0.1-0.6 µg/mL, Western Blot: 0.1 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ST2 Polyclonal Antibody. ST2 is a member of the interleukin 1 receptor family. Studies of ST2 in mouse suggested that this receptor can be induced by proinflammatory stimuli, and may be involved in the function of helper T cells. ST2 belongs to the interleukin-1 receptor family with three Ig-like C2-type (immunoglobulin-like) domains and a TIR domain. ST2 is a receptor for interleukin-33 (IL-33) which upon stimulation recruits the signaling molecules MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. Reports also suggest its possible role in helper T-cell function as well as in cell growth. Three isoforms of ST2 have been reported where isoform C is a membrane form and isoform B i |
Immunogen | n/a |
Other Names | DER4, Fit-1, IL-1 R4, IL-1RL1, IL-33R, Ly84, ST2L, ST2V, T1, suppression of tumorigenicity 2 |
Gene, Accession # | Entrez: 9173; Uniprot: Q01638 |
Catalog # | PA5-47024 |
Price | |
Order / More Info | ST2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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