产品详情 |
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Antigenic Specificity | TAB2 |
Clone | 3B5 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Flow Cytometry: 1/200 - 1/400, Western Blot: 1/500 - 1/2000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TAB2 Monoclonal Antibody (3B5). The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB , which may regulate the development and function of osteoclasts. |
Immunogen | n/a |
Other Names | CHTD2; FLJ21885; KIAA0733; MAP3K7IP2; TAB2 |
Gene, Accession # | Entrez: 23118; Uniprot: Q9NYJ8 |
Catalog # | MA5-15713 |
Price | |
Order / More Info | TAB2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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