| Edit |   |
|---|
| Antigenic Specificity | Phospho-TIRAP (Tyr86) |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human |
|---|
| Isotype | n/a |
|---|
| Format | purified |
|---|
| Size | 100 µl |
|---|
| Concentration | n/a |
|---|
| Applications | Western Blot: 1:500-1:2000 |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Phospho-TIRAP (Tyr86) Polyclonal Antibody. Adapter involved in TLR2 and TLR4 signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resulting in cytokine secretion and the inflammatory response. Positively regulates the production of TNF-alpha and interleukin-6. |
|---|
| Immunogen | n/a |
|---|
| Other Names | TIRAP; MAL; Toll/interleukin-1 receptor domain-containing adapter protein; TIR domain-containing adapter protein; Adaptor protein Wyatt; MyD88 adapter-like protein |
|---|
| Gene, Accession # | Entrez: 114609; Uniprot: P58753 |
|---|
| Catalog # | PA5-40297 |
|---|
| Price | |
|---|
| Order / More Info | Phospho-TIRAP (Tyr86) Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|