| 产品详情 |
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| Product Name | AMG 548 |
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| Description | Potent and selective inhibitor of p38α (Ki values are 0.5, 3.6, 2600 and 4100 nM for p38α, p38β, p38γ and p38δ respectively). Displays >1000-fold selectivity against 36 other kinases; inhibits whole blood LPS-stimulated TNFα (IC50 = 3 nM). Efficacious in acute and chronic models of arthritis. Purity 98%. MW (observed): 461.56 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-[[(2S)-2-Amino-3-phenylpropyl]amino]-3-methyl-5-(2-naphthalenyl)-6-(4-pyridinyl)-4(3H)-pyrimidinone |
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| Gene, Accession, CAS # | CAS: 864249-60-5 |
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| Catalog # | 3920/10 |
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| Price | |
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| Order / More Info | AMG 548 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 24086109 |
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| 产品资料 |
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