| 产品详情 |
| Edit |   |
|---|
| Product Name | AMG-47a |
|---|
| Description | AMG-47a is a potent inhibitor of Lck and T cell proliferation. It exhibits anti-inflammatory activity (ED50 = 11 mg/kg) in the anti-CD3 induced production of IL-2 in mice. In several other in vitro assays, AMG-47 displays subnanomolar inhibition against Lck, and low (<10 nM) inhibition against other hard to inhibit kinases such as KDR and SRC and MAPK α (p38α). In addition, at slightly higher doses but well under 10 µM, AMG-47 effectively inhibits the JNK family of kinases including TYK2 at ~ 1.2 µM. MW: 535.56. Purity ≥98% by HPLC |
|---|
| Size | 5 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | 4-Methyl-3-[2-[[2-(4-morpholinyl)ethyl]amino]-6-quinazolinyl]-N-[3-(trifluoromethyl)phenyl]benzamide |
|---|
| Gene, Accession, CAS # | CAS: 882663-88-9 |
|---|
| Catalog # | 2825-5 |
|---|
| Price | |
|---|
| Order / More Info | AMG-47a from BIOVISION, INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|