| 产品详情 |
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| Antigenic Specificity | CD45 |
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| Clone | CD45-2B11 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1, kappa |
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| Format | purified |
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| Size | 25 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 0.25 µg/test, Immunocytochemistry: Assay-Dependent, Immunofluorescence: Assay-Dependent, Immunohistochemistry (Paraffin): 10 µg/mL, Western Blot: 5 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD45 Monoclonal Antibody (CD45-2B11), eBioscience™. CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase (PTP) ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes. CD45 is absent on non-hematopoietic cell lines, normal and malignant, non-hematopoietic tissues. CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases. CD45 protein exists as multiple isoforms as a result of alternative splicing, differ in their extracellular domains but share identical transmembrane and cytoplasmic domains. CD45RA is an isoform of the CD45 complex and has restricted expr |
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| Immunogen | n/a |
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| Other Names | Cluster designation 45, common leukocyte antigen, T220 and B220 |
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| Gene, Accession # | Entrez: 5788; Uniprot: P08575 |
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| Catalog # | 14-9457-80 |
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| Price | |
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| Order / More Info | CD45 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 27699223 |
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