| 产品详情 |
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| Product Name | ITGB3BP, 1-216aa, Human His tag, E.coli (Denatured) |
| Description | Purity: > 90% by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol . Cntromere protein R isoform 1, also known as ITGB3BP1, is a widely expressed protein that contains a DD1 or RepD1 domain and an LXXLL motif. Induced by estrogen, ITGB3BP1 is believed to function as a nuclear receptor coactivator. It also associates with the CENP-A-CAD complex which is involved in mitotic progression, the assembly of kinetochore proteins and chromosome segregation. It acts as a transcriptional corepressor via its interaction with the NFKB1 NF-kappa-B subunit, possibly by interfering with the transactivation domain of NFKB1. Recombinant human ITGB3BP1 protein, fused to His-tag at N-terminus, was expressed in E.coli. |
| Size | 100ug, 20ug, 4ug |
| Concentration | n/a |
| Applications | SDS-PAGE |
| Other Names | Cntromere protein R isoform 1, CENP-R, CENPR, HSu37139, NRIF3, TAP20 |
| Gene, Accession, CAS # | NP 001193668 |
| Catalog # | ATGP2058 |
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| Order / More Info | ITGB3BP, 1-216aa, Human His tag, E.coli (Denatured) from ATGen |
| Product Specific References | n/a |
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