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| Product Name | DEDD, 1-318aa, Human, His tag, E.coli (Denatured) |
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| Description | Purity: > 85% by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol. Death effector domain-containing protein, also known as DEDD, is a cytoplasmic protein. It translocates to the nucleus during CD95-mediated apoptosis, where it localizes to nucleoli-like structures, activates caspase-6 and specifically inhibits RNA polymerase I-dependent transcription. The cell death activity of DEDD relates to its nuclear localization. DEDD is widely expressed in a variety of tissues, with highest levels in the testis. Overexpression of this gene was shown to induce weak apoptosis. Recombinant human DEDD protein, fused to His-tag at N-terminus, was expressed in E.coli. |
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| Size | 250ug, 50ug, 10ug |
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| Concentration | n/a |
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| Applications | SDS-PAGE |
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| Other Names | Death effector domain-containing protein, CASP8IP1, DEDD1, DEFT, FLDED1, KE05 |
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| Gene, Accession, CAS # | NP 127491 |
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| Catalog # | ATGP1945 |
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| Price | |
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| Order / More Info | DEDD, 1-318aa, Human, His tag, E.coli (Denatured) from ATGen |
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| Product Specific References | n/a |
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