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| Product Name | ECSIT, 19-217aa, Human, His tag, E.coli |
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| Description | Purity: > 90% by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol,1mM DTT . ECSIT is a ubiquitously expressed protein that plays an important role as an adaptor protein in the cytosolic signal transduction cascade events triggered by Toll receptor activation. It was initially identified as a cytoplasmic protein interacting specifically with TNF receptor associated factor (TRAF)-6 in the TLR pathway. Knockdown of ECSIT results in severely impaired complex I assembly and disturbed mitochondrial function. Recombinant human ECSIT protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
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| Size | 250ug, 50ug, 10ug |
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| Concentration | n/a |
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| Applications | SDS-PAGE |
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| Other Names | Evolutionarily conserved signaling intermediate in Toll pathway mitochondrial, Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial, SITPEC |
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| Gene, Accession, CAS # | NP 001135937 |
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| Catalog # | ATGP1745 |
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| Order / More Info | ECSIT, 19-217aa, Human, His tag, E.coli from ATGen |
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| Product Specific References | n/a |
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