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| Product Name | LRG1, 36-347aa, Human, His-tag, Baculovirus |
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| Description | Purity: > 95% by SDS - PAGE Format: Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.. LRG1, also known as leucine-rich alpha-2-glycoprotein, is a member of leucine-rich repeat (LRR) family. It is neutrophilic expressed during granulocyte differentiation. It has been shown to be involved in protein-protein interaction, signal transduction, and cell adhesion and development. It binds directly to the TGF-beta accessory receptor endoglin, which, in the presence of TGF-beta1, results in promotion of the pro-angiogenic Smad1/5/8 signaling pathway. It promotes proliferation and inhibits apoptosis in colorectal cancer cells via RUNX1 activation. It is a key physiological regulator of dendrite complexity of hippocampal pyramidal neurons. It physically interacts with TrkB and attenuates BDNF signaling. Recombinant human LRG1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
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| Size | 100ug, 20ug, 4ug |
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| Concentration | n/a |
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| Applications | SDS-PAGE |
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| Other Names | Leucine-rich alpha-2-glycoprotein, LRG1, HMFT1766, LRG |
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| Gene, Accession, CAS # | NP 443204 |
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| Catalog # | ATGP3755 |
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| Order / More Info | LRG1, 36-347aa, Human, His-tag, Baculovirus from ATGen |
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| Product Specific References | n/a |
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