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| Product Name | RPA2, 1-270aa, Human, His tag, E.coli |
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| Description | Purity: > 85 % by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 2mM DTT, 0.1M NaCl. . Replication Protein A (RPA) is a single stranded DNA binding protein. Human RPA is a heterotrimeric protein containing subunits of 14, 32 and 70kDa. This protein complex is highly conserved in eukaryotes and is essential in DNA replication, homologous recombination and nucleotide excision repair. The C-terminus of RPA2 can specfically intereact with the DNA repair enzyme uNG2 and repair factors XPA and Rad52, each of which functions in a different repair pathway. In addition, this protein binds specifically to the SH2 domain of Stat3 in vivo, and overexpression of RPA2 corresponds to the augmented growth factor-stimulated tyrosine phosphorylation and transcription activities of Stat3. Recombinant human RPA2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
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| Size | 250ug, 50ug, 10ug |
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| Concentration | n/a |
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| Applications | SDS-PAGE |
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| Other Names | Replication protein A 32 kDa subunit, Replication protein A 32 kDa subunit, REPA2, RPA32, RPA32, RP-A p32, RP-A p34 |
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| Gene, Accession, CAS # | NP 002937 |
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| Catalog # | ATGP0792 |
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| Order / More Info | RPA2, 1-270aa, Human, His tag, E.coli from ATGen |
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| Product Specific References | n/a |
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