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| Product Name | TDP1, 1-298aa, Human, His tag, E.coli (Denatured) |
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| Description | Purity: > 90% by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol . Tyrosyl-DNA phosphodiesterase 1, also known as TDP1, is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. Recombinant human TDP1, fused to His-tag at N-terminus, was expressed in E.coli. |
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| Size | 0.5mg, 100ug, 20ug |
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| Concentration | n/a |
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| Applications | SDS-PAGE |
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| Other Names | Tyrosyl-DNA phosphodiesterase 1, FLJ11090, SCAN1, Tyr-DNA phosphodiesterase 1, Tyrosyl DNA phosphodiesterase 1, TDP-1 |
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| Gene, Accession, CAS # | AAH06083 |
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| Catalog # | ATGP1950 |
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| Price | |
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| Order / More Info | TDP1, 1-298aa, Human, His tag, E.coli (Denatured) from ATGen |
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| Product Specific References | n/a |
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