| 产品详情 |
| Edit |   |
| Antigenic Specificity | Amphiregulin |
| Clone | AREG559 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1, kappa |
| Format | phycoerythrin (PE) conjugate |
| Size | 100 Tests |
| Concentration | n/a |
| Applications | Flow Cytometry: 5 µL (0.25 µg)/test |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Amphiregulin Monoclonal Antibody (AREG559), PE, eBioscience™. Amphiregulin (AR) binds to EGF-Receptor (EGFR) with lower affinity than EGF. The mature secreted form AR is an 84-amino acid residue glycosylated polypeptide growth regulator, which is generated by proteolytic processing of a 252-amino acid transmembrane precursor. Seven different polypeptide ligands, which derive from distinct genes, are capable of binding to the extracellular domain of EGFR. These ligands include EGF, TGFalpha, AR, HB-EGF, cripto-1, epiregulin, and betacellulin. All of these growth factors contain a characteristic EGF-like domain which is defined by 6 evenly spaced cysteine residues that generate 3 loops through the formation of disulfide bonds. AR protei |
| Immunogen | n/a |
| Other Names | Amphiregulin; amphiregulin B; AR; Colorectum cell-derived growth factor; CRDGF; Schwannoma-derived growth factor; SDGF |
| Gene, Accession # | Entrez: 374; Uniprot: P15514 |
| Catalog # | 12-5370-42 |
| Price | |
| Order / More Info | Amphiregulin Antibody from INVITROGEN ANTIBODIES |
| Product Specific References | n/a |
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