| 产品详情 |
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| Antigenic Specificity | CD43 |
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| Clone | eBioR2/60 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgM |
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| Format | phycoerythrin (PE) conjugate |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 0.5 µg/test |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD43 Monoclonal Antibody (eBioR2/60), PE, eBioscience™. CD43 (leukosialin, sialophorin) is a transmembrane mucin-like protein with high negative charge, expressed on the surface of most hematopoietic cells. CD43 contributes to a repulsive barrier that interferes with cellular adhesion, however, in certain cases also promotes leukocyte aggregation. By interaction with actin-binding proteins ezrin and moesin CD43 plays a regulatory role in remodeling T-cell morphology and regulates cell-cell interactions during lymphocyte traffic. CD43 signaling both enhances LFA-1 adhesiveness and counteracts LFA-1 induction via other receptors. Expression of CD43 causes induction of functionally active tumor suppressor p53 protein, but in case of p53 |
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| Immunogen | n/a |
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| Other Names | CD43, GALGP, GPL115, LSN, galactoglycoprotein, leukocyte sialoglycoprotein, leukosialin, sialophorin gpL115, leukosialin, CD43 |
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| Gene, Accession # | Entrez: 20737; Uniprot: P15702 |
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| Catalog # | 12-0431-81 |
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| Price | |
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| Order / More Info | CD43 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 18212067, 21498673, 21906575, 23148236, 23505375, 24046360, 24586648, 24719463, 25729399, 26119163, 26324445, 26833392, 26942086, 26943325, 26952187, 27609109, 28199841 |
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