| 产品详情 |
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| Antigenic Specificity | b2-microglobulin |
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| Clone | 2M2 |
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| Host Species | Mouse |
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| Reactive Species | human, African green, baboon, cynomolgus, rhesus, porcine |
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| Isotype | IgG1, κ |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC), Western Blot (WB), ELISA |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-human β2-microglobulin. β2-microglobulin (β2M) is a 12 kD nonpolymorphic Ig like protein. It is a non-membrane-anchored glycoprotein and is noncovalently associated with 39-44 kD polymorphic heavy chains of MHC class I molecules to form HLA class I antigen complex. In association with HLA class I, β2M is expressed on all leukocytes, platelets, endothelial cells, and epithelial cells. β2M plays an essential role both in governing MHC class I molecules stability and in promoting antigen binding and presenting the antigen to CD3/TCR complex of CD8+ T cells. |
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| Immunogen | Purified human β2-microglobulin |
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| Other Names | b2-M, b2M |
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| Gene, Accession # | Gene ID: 567 |
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| Catalog # | 316302 |
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| Price | |
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| Order / More Info | b2-microglobulin Antibody from BIOLEGEND |
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| Product Specific References | PubMed: 20639463,21263072,22490869 |
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