| 产品详情 |
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| Antigenic Specificity | B-Raf Phospho (Thr598/Ser601) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunofluorescence Microscopy (IF), IHC |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-B-Raf Phospho (Thr598/Ser601). The Raf proteins are a family of serine/threonine-specific kinases that serve as a central intermediate in transmitting extracellular signals to the mitogen-activated protein kinase cascade, which controls cell growth, differentiation and survival. Three isoforms of Raf proteins have been found in mammalian cells: Raf-1, A-Raf and B-Raf. The B-raf involved in signal transduction from the membrane to the nucleus. It has been reported that T598 and S601 are the major phosphorylation sites of B-Raf in response to oncogenic Ras, and phosphorylation of these two residues is required for full activation of B-Raf. Mutations in the B-Raf gene have been reported in a number of human cancers, including malignant melanoma, thyroid cancer, and colorectal carcinoma. The poly6327 antibody recognizes human phosphorylated B-Raf (Thr598/Ser601) and has been shown to be useful for immunoflorence staining. |
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| Immunogen | Modified synthetic peptide FGLATVKSRWSGS |
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| Other Names | B-Raf proto-oncogene serine/threonine-protein kinase, BRAF, p94 |
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| Gene, Accession # | n/a |
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| Catalog # | 632702 |
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| Price | |
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| Order / More Info | B-Raf Phospho (Thr598/Ser601) Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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