| 产品详情 |
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| Antigenic Specificity | CD126 |
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| Clone | UV4 |
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| Host Species | Mouse |
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| Reactive Species | human, African green, baboon, cynomolgus, rhesus |
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| Isotype | IgG1, κ |
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| Format | PE-Cy7 conjugate |
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| Size | 100 tests |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PE/Cy7 anti-human CD126 (IL-6Rα). CD126 is an 80 kD IL-6 receptor α chain also known as IL-6R. It is a member of the immunoglobulin superfamily that is expressed on plasma cells, T cells, activated B cells, monocytes, granulocytes, hepatocytes, epithelial cells, and fibroblasts. Functional IL-6 receptors are formed by the non-covalent association of CD126 and the IL-6 receptor β chain (CD130 or gp130). CD126 binds IL-6 with low affinity but does not signal. The β chain (gp130, CD130) does not bind IL-6 by itself but associates with the α-chain/IL-6 complex to initiate signal transduction. IL-6 binding to the receptor complex results in the stimulation of B and T cells, and hematopoietic precursor proliferation and differentiation. A soluble form of CD126 has been found in human serum. |
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| Immunogen | Human myeloma cell line U266 |
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| Other Names | IL-6Ra, IL-6R1, gp80, IL-6 receptor alpha |
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| Gene, Accession # | Gene ID: 3570 |
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| Catalog # | 352810 |
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| Price | |
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| Order / More Info | CD126 Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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