| 产品详情 |
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| Antigenic Specificity | CD49d |
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| Clone | 9C10 (MFR4.B) |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2a, κ |
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| Format | purified |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC), IHC |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-mouse CD49d. CD49d is a 150 kD glycoprotein, also known as α4 integrin or VLA-4 α chain. It is a member of the integrin family, expressed on T and B cells, monocytes, eosinophils, basophils, mast cells, thymocytes, NK cells, and dendritic cells. CD49d is a heterodimer expressed with either of two β chains, β1 (CD29) or β7, to form the VLA-4 (integrin α4β1) or LPAM-1 (integrin α4β7) complexes. CD49d plays a critical role in both adhesion and T cell costimulation. The primary ligands for CD49d are VCAM-1, MAdCAM-1, and fibronectin. The 9C10(MFR4.B) antibody, in combination with the R1-2 monoclonal antibody, completely blocks VCAM-1 binding to VLA-4. |
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| Immunogen | (C57BL/6 x A/J)F1 mouse fetal liver mas |
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| Other Names | α4 integrin, VLA-4 α chain, integrin a4 |
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| Gene, Accession # | Gene ID: 16401 |
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| Catalog # | 103701 |
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| Price | |
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| Order / More Info | CD49d Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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| 产品资料 |
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