| 产品详情 |
| Edit |   |
| Antigenic Specificity | CD4 |
| Clone | H129.19 |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | IgG2a, κ |
| Format | fluorescein (FITC) conjugate |
| Size | 500 µg |
| Concentration | n/a |
| Applications | Flow Cytometry (FC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | FITC anti-mouse CD4. CD4 is a 55 kD protein, also known as L3T4 or T4. It is a member of the Ig superfamily, primarily expressed on most thymocytes, a subset of T cells, and weakly on macrophages and dendritic cells. It acts as a coreceptor with the TCR during T cell activation and thymic differentiation by binding MHC class II and associating with the protein tyrosin kinase, lck. The H129.19 antibody is able to block CD4 mediated cell adhesion and T cell activation. It is also useful for in vivo and in vitro depletion of CD4+ T cells. H129.19 antibody blocks binding of the anti-mouse CD4 mAbs GK1.5 and RM4-5, but not RM4-4 antibody. H129.19 antibody inhibits various responses of T helper cells to antigenic or mitogenic stimuli. |
| Immunogen | Mouse lymphocytes |
| Other Names | L3T4, T4 |
| Gene, Accession # | Gene ID: 12504 |
| Catalog # | 130308 |
| Price | |
| Order / More Info | CD4 Antibody from BIOLEGEND |
| Product Specific References | n/a |
| 产品资料 |
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