| 产品详情 |
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| Product Name | PF-4693627 |
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| Description | An orally bioavailable mPGES-1 inhibitor (IC50 = 3 nM); selective for mPGES-1 over PGDS, TXAS, and 5-LO in HWB-1483 cells, which have IC50 values >50 µM, as well as COX-2 in fetal fibroblasts (IC50 = >10 µM); inhibits LPS-stimulated synthesis of PGE2 in human whole blood (IC50 = 109 nM); inhibits PGE2 production in a guinea pig model of carrageenan-induced air pouch inflammation (10 mg/kg) |
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| Size | 500 µg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | mPGES1 5LO lipoxygenase HWB1483 COX2 cyclooxygenase PG 04693627 PF04693627 PF4693627 |
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| Gene, Accession, CAS # | CAS: 1312815-93-2 |
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| Catalog # | 22768-500 |
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| Price | |
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| Order / More Info | PF-4693627 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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