| 产品详情 |
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| Product Name | PF-8380 |
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| Description | An inhibitor of autotaxin (IC50 = 2.8 nM in an enzyme assay); reverses leptin-induced MMP-13 expression in human OA chondrocytes at 10 µM; reduces LPA production by >95% following carrageenan-induced inflammation in rats at 30 mg/kg; inhibits autotaxin activity in human whole blood (IC50 = 101 nM) |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | autotaxin inhibitors cancers angiogenesis inflammation pains inhibits inhibitions PF8380 PF 8380 lysophospholipase D lysophosphatidylcholine LPC lysophosphatidic acids LPA carrageenan induced MMP13 |
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| Gene, Accession, CAS # | CAS: 1144035-53-9 |
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| Catalog # | 12018-10 |
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| Price | |
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| Order / More Info | PF-8380 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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