| 产品详情 |
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| Antigenic Specificity | Tuberin |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | Alexa Fluor® 594 conjugate |
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| Size | 100ul |
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| Concentration | 1ug/ul |
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| Applications | IF(IHC-P) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Tuberin Polyclonal Antibody, Alexa Fluor® 594 Conjugated. • Target Background: In complex with TSC1, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity of mTORC1. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling. Stimulates weakly the intrinsic GTPase activity of the Ras-related |
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| Immunogen | KLH conjugated synthetic peptide derived from human Tuberin. Immunogen Range: 1600-1650/1809 |
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| Other Names | LAM; TSC4; PPP1R160; Tuberin; Tuberous sclerosis 2 protein; TSC2 |
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| Gene, Accession # | Gene ID: 7249, SwissProt: P49815 |
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| Catalog # | bs-3586R-A594 |
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| Price | |
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| Order / More Info | Tuberin Antibody from BIOSS ANTIBODIES |
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| Product Specific References | n/a |
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