| 产品详情 |
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| Antigenic Specificity | CD294 (CRTH2) |
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| Clone | No3m1scz |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2a, kappa |
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| Format | Alexa Fluor 647 conjugate |
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| Size | 25 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 0.25 µg |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD294 (CRTH2) Monoclonal Antibody (No3m1scz), Alexa Fluor 647, eBioscience™. The prostaglandin D2 receptor 2 (PTGDR2), also known as CRTH2, is expressed on Th2 cells and eosinophils and mediates chemotaxis of these cells to PGD2 and is thus thought to be a key receptor mediating eosinophil and Th2 recruitment during allergic responses. However, PTGDR2-null mice showed enhanced eosinophil recruitment into the lung consistent with observations that the PTGDR2-null mice produced significantly higher amounts of interleukin-5 (IL-5) and IL-3. This suggests that PTGDR2 plays a nonredundant role in restricting eosinophilia and allergic response in vivo. |
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| Immunogen | n/a |
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| Other Names | CRTH2, DP2, PD2R2, GPR44, DL1R |
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| Gene, Accession # | Entrez: 14764; Uniprot: Q9Z2J6 |
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| Catalog # | 51-2941-80 |
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| Price | |
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| Order / More Info | CD294 (CRTH2) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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