| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | CD294 (CRTH2) |
|---|
| Clone | No3m1scz |
|---|
| Host Species | Rat |
|---|
| Reactive Species | mouse |
|---|
| Isotype | IgG2a, kappa |
|---|
| Format | Alexa Fluor 647 conjugate |
|---|
| Size | 100 µg |
|---|
| Concentration | n/a |
|---|
| Applications | Flow Cytometry: 0.25 µg |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | CD294 (CRTH2) Monoclonal Antibody (No3m1scz), Alexa Fluor 647, eBioscience™. The prostaglandin D2 receptor 2 (PTGDR2), also known as CRTH2, is expressed on Th2 cells and eosinophils and mediates chemotaxis of these cells to PGD2 and is thus thought to be a key receptor mediating eosinophil and Th2 recruitment during allergic responses. However, PTGDR2-null mice showed enhanced eosinophil recruitment into the lung consistent with observations that the PTGDR2-null mice produced significantly higher amounts of interleukin-5 (IL-5) and IL-3. This suggests that PTGDR2 plays a nonredundant role in restricting eosinophilia and allergic response in vivo. |
|---|
| Immunogen | n/a |
|---|
| Other Names | CRTH2, DP2, PD2R2, GPR44, DL1R |
|---|
| Gene, Accession # | Entrez: 14764; Uniprot: Q9Z2J6 |
|---|
| Catalog # | 51-2941-82 |
|---|
| Price | |
|---|
| Order / More Info | CD294 (CRTH2) Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|