| Edit |   |
|---|
| Antigenic Specificity | CD273 (B7-DC) |
|---|
| Clone | 122 |
|---|
| Host Species | Rat |
|---|
| Reactive Species | mouse |
|---|
| Isotype | IgG2a, kappa |
|---|
| Format | Super Bright 436 conjugate |
|---|
| Size | 100 µg |
|---|
| Concentration | n/a |
|---|
| Applications | Flow Cytometry: 1.0 µg/test |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | CD273 (B7-DC) Monoclonal Antibody (122), Super Bright 436, eBioscience™. Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by co gnate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2, both of which are thought act as a negative regulator of T cell activation. However, it has been suggested that PDL-2 can act to stimulate an immunogenic response through and alternative receptor from PD-1. At least three isoforms of PDL-2 are known to exist; this ant |
|---|
| Immunogen | n/a |
|---|
| Other Names | B7-DC; B7dc; Btdc; Cd273; F730015O22Rik; PD-L2; Pdcd1lg2; Pdl2 |
|---|
| Gene, Accession # | Entrez: 58205; Uniprot: Q9WUL5 |
|---|
| Catalog # | 62-9972-82 |
|---|
| Price | |
|---|
| Order / More Info | CD273 (B7-DC) Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|