| 产品详情 |
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| Antigenic Specificity | Thymidine Phosphorylase |
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| Clone | PGF-44C |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Frozen): Assay Dependent, Immunoprecipitation: Assay Dependent, Western Blot: Assay Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Thymidine Phosphorylase Monoclonal Antibody (PGF-44C). Platelet - derived endothelial growth factor (PD-ECGF), same as thymidine phosphorylase (TP) or gliostatin. In the presence of inorganic orthophosphate, it catalyses the reversible phospholytic cleavage of thymidine and deoxyuridine to their correspondingbases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. It is also invoved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites. |
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| Immunogen | n/a |
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| Other Names | ECGF, ECGF1, MEDPS1, MNGIE, MTDPS1, PDECGF, TP, hPD-ECGF, gliostatin, tdRPase |
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| Gene, Accession # | Entrez: 1890; Uniprot: P19971 |
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| Catalog # | 35-5700 |
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| Price | |
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| Order / More Info | Thymidine Phosphorylase Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 19513500, 21170649, 21896999 |
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