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| Product Name | Recombinant Human CDC37 |
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| Description | Molecular weight of approximately 44.5kDa. Scientific Background: Hsp90 co-chaperone Cdc37 is a protein that is encoded by the CDC37 gene. It has been found to form complexes with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF1, MOK and elF-2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases (1, 2). CDC37 is necessary for maintaining prostate tumor cell growth and represents a novel target in the exploration for multi-targ |
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| Size | 0.05 mg |
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| Concentration | 1mg/mL |
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| Applications | Western Blot (WB) control, functional/activity studies |
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| Other Names | [hsp90 co-chaperone Cdc37; Hsp90 co-chaperone Cdc37; hsp90 co-chaperone Cdc37; cell division cycle 37 homolog; CDC37 cell division cycle 37 homolog; hsp90 chaperone protein kinase-targeting subunit; CDC37 (cell division cycle 37, S. cerevisiae, homolog); cell division cycle 37; Hsp90 chaperone protein kinase-targeting subunit; p50Cdc37Cleaved into the following chain:Hsp90 co-chaperone Cdc37, N-terminally processed] |
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| Gene, Accession, CAS # | CDC37; CDC37; P50CDC37; CDC37A, Gene ID: 11140, Accession: NP_008996.1 |
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| Catalog # | MBS806930 |
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| Order / More Info | Recombinant Human CDC37 from MYBIOSOURCE INC. |
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| Product Specific References | 1. Dai K, Kobayashi R., Beach D. (1996) J Biol Chem. 271(36): 22030-22034. 2. Stepanova L, Leng X., Parker S.B., Harper J.W. (1996) Genes Dev. 10(12): 1491-1502. 3. Kimura Y., et al. (1997) Genes Dev. 11(14): 1775-1185. 4. Gray P.J., et al. (2008) Nat Rev Cancer. 8(7): 491-495. |
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