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| Product Name | D-2-Hydroxyglutarate (D2HG) Assay Kit (Colorimetric) |
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| Description | Background/Introduction: In eukaryotic cells, Isocitrate Dehydrogenase (IDH1, IDH2 and IDH3) catalyzes the interconversion of Isocitrate and alpha-Ketoglutarate. In human cancers, an IDH mutation causes a gain-of-function, which reduces its affinity for isocitrate and facilitates the conversion of alpha-ketoglutarate to D-2-Hydroxyglutarate in the presence of NADP. D-2-Hydroxyglutarate (D2HG) is present at low level in normal cells and tissues, but is significantly elevated in metabolic diseases |
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| Size | 100 assays |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | D2HG |
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| Catalog # | MBS846584 |
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| Order / More Info | D-2-Hydroxyglutarate (D2HG) Assay Kit (Colorimetric) from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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