| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | CD274 (PD-L1, B7-H1) |
|---|
| Clone | MIH5 |
|---|
| Host Species | Rat |
|---|
| Reactive Species | mouse |
|---|
| Isotype | IgG2a, lambda |
|---|
| Format | PE-Cyanine7 conjugate |
|---|
| Size | 100 µg |
|---|
| Concentration | n/a |
|---|
| Applications | Flow Cytometry: 0.125 µg/test |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | CD274 (PD-L1, B7-H1) Monoclonal Antibody (MIH5), PE-Cyanine7, eBioscience™. Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a recently described B7 family member. To date, one specific receptor has been identified that can be ligated by PD-L1. This receptor, programmed death receptor 1 (PD-1), has been shown to negatively regulate T-cell receptor (TCR) signaling. Upon ligating its receptor, PD-L1 has been reported to decrease TCR-mediated proliferation and cytokine production. PD-L1 expression was found to be abundant on many murine and human cancers and could be further up-regulated upon IFN-gamma stimulation. Thus, PD-L1 might play an important role in tumor immune evasion. |
|---|
| Immunogen | n/a |
|---|
| Other Names | B7-H, B7H1, PD-L1, PDCD1L1, PDCD1LG1, PDL1, B7 homolog 1, CD274 antigen, PDCD1 ligand 1, programmed cell death 1 ligand 1, programmed death ligand 1 |
|---|
| Gene, Accession # | Entrez: 60533; Uniprot: Q9EP73 |
|---|
| Catalog # | 25-5982-82 |
|---|
| Price | |
|---|
| Order / More Info | CD274 (PD-L1, B7-H1) Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | PubMed: 18607390, 21816363, 21873557, 27156385, 28611299, 29246442, 29593314, 29846432 |
|---|
| 产品资料 |
|
|