| 产品详情 |
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| Antigenic Specificity | B7-DC (CD273, PD-L2, PDL2, B7DC) |
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| Clone | TY25 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2a, κ |
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| Format | purified, azide-free |
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| Size | 500 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC), Western Blot (WB) , IP, Block, IHC |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | LEAF™ Purified anti-mouse CD273 (B7-DC, PD-L2). B7-DC is also called programmed death ligand 2 (PDL2). It has recently been clustered as CD273. This ligand is a 42 kD member of the immunoglobulin receptor superfamily expressed on a subset of dendritic cells, liver and a small subset of macrophages as well as a few transformed cell lines. CD273 has been reported to be stimulatory on dendritic cells when cross-linked and to inhibit T cell activation upon engaging the PD-1 receptor. CD273 has also been reported to bind to an alternative receptor and to mediate T cell activation through such non-PD1 mediated interactions. The TY25 antibody has been reported to be useful for blocking PD-1 mediated interactions. |
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| Immunogen | Mouse B7-DC transfected cell line |
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| Other Names | PDL2, B7DC |
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| Gene, Accession # | Gene ID: 58205 |
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| Catalog # | 107208 |
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| Price | |
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| Order / More Info | B7-DC (CD273, PD-L2, PDL2, B7DC) Antibody from BIOLEGEND |
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| Product Specific References | PubMed: 17003438,21276089,24039898 |
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