| 产品详情 |
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| Antigenic Specificity | CD27 Molecule (CD27) |
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| Clone | 137B4 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | supernatant |
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| Size | 0.5 mL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD27 is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells (1). It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily (2). CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell costimulation and B-cell activation (3,4). It also interacts with TRAFs and is involved in activation of NFκB and SAPK/JNK and induces apoptosis (5-7).Synonyms: CD27L receptor, T-cell activation antigen CD27, T14, TNFRSF7, Tumor necrosis factor receptor superfamily member 7 |
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| Immunogen | Recombinant human CD27 proteinRemarks: Mol. Wt. of Antigen: 120 kDa |
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| Other Names | TNFRSF7|S152|Tnfrsf7|Tp55|S152. LPFS2|T14 |
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| Gene, Accession # | Gene ID: 939 |
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| Catalog # | ABIN180648 |
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| Price | |
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| Order / More Info | CD27 Molecule (CD27) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 9298683, 8759195, 7573360 |
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