| 产品详情 |
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| Antigenic Specificity | CTLA-4 (CD152) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | lyophilized |
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| Applications | ELISA: Assay-dependent, Immunohistochemistry (Paraffin): 1 µg/mL, Western Blot: 0.5 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CTLA-4 (CD152) Polyclonal Antibody. CTLA-4 (Cytotoxic T-Lymphocyte Antigen 4), also known as CD152, is a protein receptor that down regulates the immune system. It is a member of the immunoglobulin superfamily, which is expressed on the surface of Helper T cells and transmits an inhibitory signal to T cells. CTLA4 is similar to the T-cell co-stimulatory protein, CD28, and both molecules bind to CD80 and CD86, also called B7-1 and B7-2 respectively, on antigen-presenting cells. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Blockade of CTLA4 expression in vitro augmented HIV-specific CD4-positive T-cell function. |
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| Immunogen | n/a |
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| Other Names | Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4, CTLA-4, CD152, Ctla4, Cd152 |
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| Gene, Accession # | Entrez: 12477, 63835; Uniprot: P09793 |
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| Catalog # | PA5-79090 |
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| Price | |
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| Order / More Info | CTLA-4 (CD152) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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