| 产品详情 |
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| Antigenic Specificity | IL-17A |
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| Clone | 50101 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2a |
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| Format | purified |
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| Size | 500 µg |
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| Concentration | lyophilized |
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| Applications | ELISA: 0.1-0.4 µg/mL (Detection), 2-8 µg/mL (Capture), Western Blot: 1 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | IL-17A Monoclonal Antibody (50101). Interleukin-17A (IL-17A, CTLA-8) is a CD4+ T cell-derived cytokine that promotes inflammatory responses in cell lines and is elevated in rheumatoid arthritis, asthma, multiple sclerosis, psoriasis, and transplant rejection. IL-17A is a 32 kDa long, disulfide-linked homodimer consisting of 136 amino acids that is a member of a six-species family of proteins (IL-17A-17F) and signals through the IL-17 receptor (IL-17R/CDw217). High levels of IL-17A homodimer are produced by activated peripheral blood CD4+ T-cells, and IL-17A also enhances expression of the intracellular adhesion molecule-1 (ICAM-1) in human fibroblasts. In particular, human IL-17A also stimulates epithelial, endothelial, or fibroblastic cell |
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| Immunogen | n/a |
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| Other Names | CTLA8, IL17, interleukin 17, cytotoxic T-lymphocyte-associated serine esterase 8, Interleukin-17A |
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| Gene, Accession # | Entrez: 16171; Uniprot: Q62386 |
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| Catalog # | MA5-23747 |
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| Price | |
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| Order / More Info | IL-17A Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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