产品详情 |
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Antigenic Specificity | IL-17A |
Clone | eBio17B7 |
Host Species | Rat |
Reactive Species | mouse, rat |
Isotype | IgG2a, kappa |
Format | allophycocyanin (APC) conjugate |
Size | 50 µg |
Concentration | n/a |
Applications | Flow Cytometry: 0.125 µg/test |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | IL-17A Monoclonal Antibody (eBio17B7), APC, eBioscience™. Interleukin-17A (IL-17A, CTLA-8) is a CD4+ T cell-derived cytokine that promotes inflammatory responses in cell lines and is elevated in rheumatoid arthritis, asthma, multiple sclerosis, psoriasis, and transplant rejection. IL-17A is a 32 kDa long, disulfide-linked homodimer consisting of 136 amino acids that is a member of a six-species family of proteins (IL-17A-17F) and signals through the IL-17 receptor (IL-17R/CDw217). High levels of IL-17A homodimer are produced by activated peripheral blood CD4+ T-cells, and IL-17A also enhances expression of the intracellular adhesion molecule-1 (ICAM-1) in human fibroblasts. In particular, human IL-17A also stimulates epithelial, endot |
Immunogen | n/a |
Other Names | Interleukin-17 |
Gene, Accession # | Entrez: 16171, 301289; Uniprot: Q61453, Q62386 |
Catalog # | 17-7177-81 |
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Order / More Info | IL-17A Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 19542365, 19542441, 19635913, 20061408, 20488794, 20733201, 20886077, 20952591, 21074460, 21094688, 21131367, 21589883, 21647171, 21715314, 21806815, 21856864, 22225602, 22430492, 22450809, 22464170, 22732586, 22888330, 23077616, 23159881, 23315072, 23316306, 23359509, 23592971, 23644504, 23776551, 23852275, 23858031, 23864512, 23941891, 24100657, 24145030, 24591364, 24600029, 24646939, 25182415, 25267971, 25490199, 25556169, 25642823, 25658831, 25662996, 25694610, 25766071, 25896324, 25902191, 25941359, 26002979, 26125554, 26307665, 26317210, 26321145, 26324767, 26348529, 26583087, 26621452, 26647186, 26656646, 26809474, 26936133, 27007676, 27040495, 27109934, 27173727, 27245356, 27288531, 27311945, 27315465, 27606424, 27716507, 27853305, 28087667, 28193608, 28411140, 28560450, 28747917, 28768901, 28768912, 28944907, 29042531, 29123203, 29375374, 29403003, 29434788, 29650963 |
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