产品详情 |
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Antigenic Specificity | IL-17A |
Clone | eBio17B7 |
Host Species | Rat |
Reactive Species | mouse, rat |
Isotype | IgG2a, kappa |
Format | fluorescein (FITC) conjugate |
Size | 50 µg |
Concentration | n/a |
Applications | Flow Cytometry: 0.25 µg/test, Immunohistochemistry (Paraffin): Assay-Dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | IL-17A Monoclonal Antibody (eBio17B7), FITC, eBioscience™. Interleukin-17A (IL-17A, CTLA-8) is a CD4+ T cell-derived cytokine that promotes inflammatory responses in cell lines and is elevated in rheumatoid arthritis, asthma, multiple sclerosis, psoriasis, and transplant rejection. IL-17A is a 32 kDa long, disulfide-linked homodimer consisting of 136 amino acids that is a member of a six-species family of proteins (IL-17A-17F) and signals through the IL-17 receptor (IL-17R/CDw217). High levels of IL-17A homodimer are produced by activated peripheral blood CD4+ T-cells, and IL-17A also enhances expression of the intracellular adhesion molecule-1 (ICAM-1) in human fibroblasts. In particular, human IL-17A also stimulates epithelial, endo |
Immunogen | n/a |
Other Names | Interleukin-17 |
Gene, Accession # | Entrez: 16171, 301289; Uniprot: Q61453, Q62386 |
Catalog # | 11-7177-81 |
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Order / More Info | IL-17A Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 19188681, 19332874, 19542441, 19635913, 21094688, 21307296, 21589883, 21806815, 21996276, 22732586, 23077616, 23418628, 23626013, 23644504, 23941891, 24205109, 24420551, 24631024, 24634494, 25024136, 25087995, 25385367, 25490199, 25556169, 25902191, 26002979, 26006007, 26130142, 26317210, 26321145, 26324767, 26544846, 26644347, 26647186, 26656646, 27007676, 27245356, 27315465, 27337687, 27425374, 27716507, 27736987, 27853305, 28008946, 28087667, 28411140, 28560450, 28768901, 28768912, 28944907, 29042531, 29257087, 29375374, 29434788 |
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