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| Product Name | NCK Adaptor Protein 1 (NCK1) (AA 1-377) protein (His tag) |
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| Description | Cytoplasmic Protein NCK1 (NCK1) is a cytoplasmic protein that contains one SH2 domain and three SH3 domains. NCK1 is a member of the adapter family, which associates with tyrosine-phosphorylated growth factor receptors, such as KDR and PDGFRB, or their cellular substrates. NCK1 maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. NCK1 plays a role in the DNA damage response, but not in the detection of the damage by ATM/ATR. It is also involved in transducing signals from receptor tyrosine kinases to downstream signal recipients, such as ELK1-dependent transcriptional activation in response to activated Ras signaling.Alternative Names: Cytoplasmic Protein NCK1, NCK adaptor Protein 1, Nck-1, SH2/SH3 Adaptor Protein NCK-Alpha, NCK1, NCK |
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| Size | 500 µg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | NCK1|NCK|NCKalpha|nck-1|6330586M15Rik|D230010O13Rik|Nck|Nck-1 |
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| Gene, Accession, CAS # | Gene ID: 4690 |
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| Catalog # | ABIN1692084 |
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| Order / More Info | NCK Adaptor Protein 1 (NCK1) (AA 1-377) protein (His tag) from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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