产品详情 |
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Antigenic Specificity | CD278 (ICOS) |
Clone | C398.4A |
Host Species | Armenian Hamster |
Reactive Species | mouse, rat, rhesus monkey |
Isotype | IgG |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Flow Cytometry: 0.25 µg/test, Functional Assay: Assay-Dependent, Immunohistochemistry: Assay-Dependent, Immunoprecipitation: Assay-Dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD278 (ICOS) Monoclonal Antibody (C398.4A), eBioscience™. CD278 belongs to the CD28 and CTLA-4 cell-surface receptor family and is highly expressed in activated T-cells. It is essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. It enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. |
Immunogen | n/a |
Other Names | AILIM, CD278, CVID1, activation-inducible lymphocyte immunomediatory molecule, inducible T-cell costimulator, inducible costimulator |
Gene, Accession # | Entrez: 54167, 64545, 705788; Uniprot: Q9R1T7, Q9WVS0 |
Catalog # | 14-9949-82 |
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Order / More Info | CD278 (ICOS) Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 19299705, 21209284, 21708958, 23024058, 23729441, 24168764, 25692700, 26026061, 26214741, 28402334 |
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