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| Product Name | Recombinant Mouse Phorbol-12-myristate-13-acetate-induced protein 1 (Pmaip1) |
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| Description | Purity > 85% as determined by SDS-PAGE. MW: 15.6kDa. Full Length: 1-103aa. N-terminal 6xHis-tagged. Mus musculus (Mouse). Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Protein Noxa (Noxa) |
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| Gene, Accession, CAS # | Pmaip1, UniProt: Q9JM54 |
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| Catalog # | RPC26235 |
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| Order / More Info | Recombinant Mouse Phorbol-12-myristate-13-acetate-induced protein 1 (Pmaip1) from BIOMATIK |
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| Product Specific References | n/a |
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