产品详情 |
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Product Name | PD 089828 |
Description | An inhibitor of EGFR, PDGFβ, FGF, and c-Src (IC50s = 0.15, 1.76, 5.47, and 0.18 µM, respectively); inhibits MAPK (IC50 = 7.1 µM); selective over insulin receptor tyrosine kinase, PKC, and CDK4 (IC50s = >50 µM); decreases PDGF-BB-, EGF-, and bFGF-induced phosphorylation of PDGFR, EGFR, and FGFR1 in vitro; decreases serum-stimulated growth (IC50 = 1.8 µM after 8 days) and migration (IC50 = 4.5 µM) of rat aortic smooth muscle cells |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | EGF/FGF/PDGF Receptor Tyrosine Kinase Inhibitor |
Gene, Accession, CAS # | CAS: 179343-17-0 |
Catalog # | 21435-1 |
Price | |
Order / More Info | PD 089828 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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