| 产品详情 |
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| Product Name | PD 166793 |
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| Description | An broad-spectrum MMP inhibitor (IC50s = 6.1, 0.047, 0.012, 7.2, 7.9, 0.008, and 0.24 µM for MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP13CD, and MMP-14CD, respectively); reverses peroxynitrite-induced decreases in contraction cease time in isolated rat ventricular myocytes at 2 µM; reduces LV peak wall stress in a porcine model of congestive heart failure at 2 mg/kg per day; reduces LV dilation and preserves systolic function in a rat model of progressive heart failure; inhibits age-associated increases in aortic gelatinase and interstitial collagenase activity and mean arterial pressure in rats, |
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| Size | 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | PD166793 166793-0000 PD166793-0000 MMP1 MMP2 MMP3 MMP7 MMP9 MMP13CD 13-CD MMP14CD 14-CD |
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| Gene, Accession, CAS # | CAS: 199850-67-4 |
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| Catalog # | 23762-25 |
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| Order / More Info | PD 166793 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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