| 产品详情 |
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| Antigenic Specificity | LATS1 |
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| Clone | 2H43L6 |
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| Host Species | Recombinant Rabbit |
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| Reactive Species | human |
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| Isotype | IgG |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blot: 1-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | LATS1 Antibody (2H43L6), ABfinity™ Rabbit Monoclonal. LATS1 is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is phosphorylated in a cell-cycle dependent manner, with late prophase phosphorylation remaining through metaphase. The N-terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity, indicating a role as a negative regulator of CDC2/cyclin A. In addition, the C-terminal kinase domain binds to its own N-terminal region, suggesting potential negative regulation through interference with complex formation via intramolecular binding. Biochemical and genetic data suggest a role as |
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| Immunogen | n/a |
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| Other Names | WARTS Protein Kinase |
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| Gene, Accession # | Entrez: 9113; Uniprot: O95835 |
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| Catalog # | 702117 |
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| Price | |
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| Order / More Info | LATS1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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